Fig. 3: Applying IREDs for analytical-scale synthesis of APIs′ substructures.
From: Actinomycetes-derived imine reductases with a preference towards bulky amine substrates

a Reductive aminations of 4 with B, D, and E. b Reductive aminations of 3 with B and C. c Reductive amination of 5 with F. d Reductive aminations of 1, 5, 6, and 7 with C and G. e Reductive aminations of 2 and 6 with C, D, and H. f Reductive aminations of 8 and 9 with I.