Table 2 Interplay between ionic strength, pH, and Zn2+ for Aβ fibrillation.

From: Multivariate effects of pH, salt, and Zn2+ ions on Aβ40 fibrillation

Zn2+

Impact of pH Increase

Impact of NaCl

Absence

Promote fibrillation

Promote fibrillation

Presence

Inhibit fibrillation

Inhibit fibrillation at pH 6

  

Promote fibrillation at pH 8