Fig. 1: Overview of this study and its precedent.
From: A spirocyclic backbone accesses new conformational space in an extended, dipole-stabilized foldamer
a Dipole-controlled foldamer allowing control of backbone shape by changing yaw angle. Localised dipoles are indicated (maroon arrows). b Previous foldamers incorporating spircocyles. c The merging of a spirocyclic monomer with the dipole-controlled foldamer concept can allow greater exploration of conformational space, and side-chain vectors along multiple axes.
