Fig. 5: Active site comparisons.
From: Structure of a 10-23 deoxyribozyme exhibiting a homodimer conformation
A active site of 10-23 DNAzyme crystal structure. B Proposed base-flip conformational change that aligns the 2′-OH to the scissile phosphate for ‘in-line’ attack. C Alignment of the 10-23 DNAzyme crystal structure active site (blue) and the NMR 10-23 DNAzyme active site (yellow).
