Fig. 4: Asymmetric synthesis of morpholin-2-ones with multi-stereocenters.[a]

[a] Conditions: 1 (0.10 mmol), 2 (0.12 mmol), ZnCl2 (0.02 mmol), DCE (c 0.1 M), sealed tube, argon, 12 h. [b] Yield of 1.0 mmol scale.

[a] Conditions: 1 (0.10 mmol), 2 (0.12 mmol), ZnCl2 (0.02 mmol), DCE (c 0.1 M), sealed tube, argon, 12 h. [b] Yield of 1.0 mmol scale.