Fig. 1: Telomeres and the telomeres’ proteome. | Communications Chemistry

Fig. 1: Telomeres and the telomeres’ proteome.

From: Conformational plasticity and allosteric communication networks explain Shelterin protein TPP1 binding to human telomerase

Fig. 1

a Telomeres are portions of noncoding DNA located at the chromosome termini. b The Telomerase ribonucleoprotein, composed of the enzyme TERT (green) and the telomeric RNA TR (pink). c The 6-membered Shelterin complex, composed of the double-strand binding proteins RAP1 (red), TRF2 (yellow), TRF1 (orange), and TIN2 (dodger-blue), together with the single-strand binding proteins TPP1 (gray) and POT1 (magenta).

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