Fig. 6: Solvent-independent guest encapsulation in the Ag₅L₂ cage.

a Schematic representation of the host–guest chemistry of Hg₅L₂ in different solvents or solvent mixture. In all the studied solvent systems, including CDCl₂CDCl₂, the Hg₅L₂ cages can encapsulate the guests to form stable host–guest complexes. b ¹H NMR spectra (600 MHz, 298 K, 1 mM, CD₃CN) of (i) Hg₅L₂, (ii) Ad⊂Hg₅L₂ in the presence of 8 equiv. of Ad (prepared via Procedure A), and (iii) Ad⊂Hg₅L₂ in the absence of free Ad after the solution was stored at 298 K for 2 days. c ¹H NMR spectra (600 MHz, 298 K, 1 mM CDCl₂CDCl₂) of (i) Hg₅L₂, (ii) Ad⊂Hg₅L₂ in the presence of 200 equiv. of Ad (prepared via Procedure E), and (iii) Ad⊂Hg₅L₂ in the absence of free Ad after the solution was kept at 298 K for 2 days. For experimental details, see Methods.