Table 1 l-Lactate biosensors used in this work

From: Synthesis and application of a photocaged-l-lactate for studying the biological roles of l-lactate

 

Color

Localization

Kd (μM)

F/F

eLACCO123

Green

Extracellular membrane

4.1

6

deLACCO130

Control that is not responsive to l-lactate

eLACCO2.130

580

8.8

R-iLACCO1.230

Red

Cytosol

4000

11

R-diLACCO130

Control that is not responsive to l-lactate

  1. Kd and ∆F/F values for eLACCO2.1 and R-iLACCO1.2 are the previously reported values based on fluorescence imaging of live cells treated with l-Lactate.