Fig. 3: Results of the initial screening by DSF and SPR.
From: A bottom-up approach to find lead compounds in expansive chemical spaces
a Results of the single dose screening at 10 µM by DSF showing the number of compounds grouped by the degrees of thermal shift of BRD4 (BD1). b Results of the single dose screening at 10 µM by SPR showing the number of compounds grouped by the significance obtained compared to the average of the blanks. c Venn diagrams combining the results obtained by DSF and SPR grouped by the different initial scenarios.
