Fig. 1: Chemical and radiochemical analogues studied. | Communications Chemistry

Fig. 1: Chemical and radiochemical analogues studied.

From: Development and characterisation of novel oxytocin analogues for PET imaging

Fig. 1

A Chemical structures of studied OT analogues and respective synthetic route. Aoa = aminooxy acetic acid; SFB = N-succinimidyl-4-fluorobenzoate; FDG = fluorodeoxyglucose (acyclic aldehyde representation); ESF = ethenesulfonylfloride; FBA = 4-Fluorobenzaldehyde. B Reaction scheme for the radioconjugation of dOTK8 using [18F]SFB. Aspects that were varied during optimisation are highlighted under the reaction arrow.

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