Fig. 6: Cross-platform analysis of age-associated proteins and pathways. | Communications Chemistry

Fig. 6: Cross-platform analysis of age-associated proteins and pathways.

From: Current landscape of plasma proteomics from technical innovations to biological insights and biomarker discovery

Fig. 6

a UpSet plot showing the intersection of significant (p-adj < 0.05) age markers identified by each platform. b Results of pathway enrichment analysis using significant age markers from each platform and the union of proteins across all platforms as a background. GO, KEGG and Reactome pathway analysis of significant age markers from each of the platforms. Each bubble represents a term, and the size of the bubble indicates the number of markers involved. Only terms with significant (p-adj < 0.01) and at least 10 markers are shown. c UpSet plot showing the intersection of significant age-related pathways identified across platforms. Only terms with significant (p-adj < 0.01) and at least 10 markers are shown.

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