Fig. 3: Phase separation-induced amyloid formation of N-terminally truncated α-syn. | Communications Chemistry

Fig. 3: Phase separation-induced amyloid formation of N-terminally truncated α-syn.

From: Surface wetting is a key determinant of α-synuclein condensate maturation

Fig. 3: Phase separation-induced amyloid formation of N-terminally truncated α-syn.The alternative text for this image may have been generated using AI.

a Normalized ThT intensity of 5-140 (red), 11-140 (green) or 19-140 (purple) α-syn shown alongside the FL α-syn data (semi-transparent blue) as comparison. Each repeat is the mean of three technical replicates; error bars represent the standard deviation of the mean. b Representative DIC, ThT fluorescence, and TEM images taken at the bottom of the well at the endpoint of the assay. The fluorescence scale bars represent 25 μm; the TEM scale bars represent 3 μm.

Back to article page