Table 2 Functionalization strategies with various ligands or specific (bio) receptors in polydiacetylene (PDA)-based colorimetric sensors and their analytical performances

From: Surface functionalization strategies for polydiacetylene-based colorimetric sensors

Target analyte

Specific (bio)receptors

Detection technique

Sensing time (min)

Linear range

Limit of detection

References

Salmonella Typhimurium bacterium

Aptamer

Colorimetric (CR% value)

15

103–107 CFU mL−1

103 CFU mL−1

7

Zn2+

Aptamer

Colorimetric (RCS% value)

240

0–1000 µM

125 µM

139

E. coli O157:H7, S. Typhimurium, V. parahaemolyticus

Aptamer

Colorimetric (CR% value)

30

E. coli O157:H7 (10–107 CFU mL−1), S. Typhimurium (10─106 PFU mL−1), V. parahaemolyticus (10–106 PFU mL−1)

E. coli O157:H7 (39 CFU mL−1), S. Typhimurium (60 PFU mL−1), V. parahaemolyticus (60 PFU mL−1)

43

Bacillus thuringiensis HD-73 Spores

Aptamer

Colorimetric (CR% value)

240

3 × 107–3 × 1011 PFU mL−1

3 × 107 CFU mL−1

44

Thrombin

Aptamer

Colorimetric (CR% value)

15

0–10 µM

0.5 µM

140

Genes

Oligonucleotide

Colorimetric (CR% value)

NA

0–20 µM

NA

141

Exosome

Antibody

Colorimetric (CR% value) and fluorescence

30

3 × 107–1 × 1010 vesicles mL-1

3 × 108 vesicles mL−1

142

Pb2+ or volatile organic compounds (VOCs)

Amino acids (histidine)

Colorimetric (CR% value) and fluorescence

0.12

0–37 μM

Pb2+ (0.04 µM)

69

Trinitrotoluene (TNT)

Peptide

Colorimetric (CR% value)

NA

5.2–33.6 µM

NA

39

Adenosine triphosphate (ATP)

Tripeptide-based Zn (II) complex

Colorimetric (absorbance)

NA

NA

NA

143

E. Coli

Glycolipids

Colorimetric (absorbance)

NA

NA

NA

144

Free fatty acid (FFA)

Phospholipid

Colorimetric (CR% value)

1440

0–2.5 mg mL−1

NA

145

Cd2+

Ligand chelator

Colorimetric (absorbance) and fluorescence

1

NA

NA

146

Streptavidin (protein)

Biotin

Colorimetric (absorbance) and fluorescence

1

NA

NA

104

  1. Colorimetric response percentage (CR%), red chromatic shift percentage (RCS%), absorbance, and fluorescence are typically used as the detection methods or parameters.