Cholesterol accumulation in cells and blood vessels promotes the development of vascular diseases. The long non-coding RNA CHROME can help clear excess cholesterol and provide protection from atherosclerosis.
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Sallam, T., Tontonoz, P. Lnc-ing microRNA activity to atheroprotection. Nat Metab 1, 10–11 (2019). https://doi.org/10.1038/s42255-018-0012-9
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DOI: https://doi.org/10.1038/s42255-018-0012-9
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Long noncoding RNAs in familial hypercholesterolemia: biomarkers, therapeutics, and AI in precision medicine
Lipids in Health and Disease (2025)