Extended Data Fig. 1: Platelet counts in 4-month oral toxicity studies of PF-05175157 in rats and dogs.
From: De novo lipogenesis is essential for platelet production in humans
a, platelet counts in male and female Wistar Han rats on day 118. N=10 per group. Wistar Han rats were from Charles River Laboratories 8–9 wks old. b, platelet counts in male and female dogs during pre-study (day -13) and day 114. N=3 per sex per group. Dogs were Beagles (male and female) from Marshal Farms > 8 months old. Data are mean ± standard deviation. Symbols represent individual values.
