Extended Data Fig. 5: Physiological characteristics of mice used for scRNA-seq.
From: Targeted pharmacological therapy restores β-cell function for diabetes remission
Representative mice (n = 3) of each treatment were used for scRNA-seq. a, Fasting glucose levels. One-way ANOVA with Tukey post-hoc test among mSTZ, oestrogen, GLP-1 and GLP- 1/oestrogen treated mice (F (3, 8) = 21.23). One-way ANOVA with Tukey post-hoc among no STZ, GLP-1/oestrogen, PEG-insulin, and co-treated mice (F (3, 8) = 94.06). b, Fasting C-peptide levels. One-way ANOVA with Tukey post-hoc test among STZ, oestrogen, GLP-1 and GLP- 1/oestrogen treated mice (F (3, 8) = 9.073). All data are mean ± SEM.
