Extended Data Fig. 9: Eosinophil transfers reverse myeloid skewing in old age. | Nature Metabolism

Extended Data Fig. 9: Eosinophil transfers reverse myeloid skewing in old age.

From: Eosinophils regulate adipose tissue inflammation and sustain physical and immunological fitness in old age

Extended Data Fig. 9: Eosinophil transfers reverse myeloid skewing in old age.

a, Gating strategy for the identification of LSK, HSC-SLAM, HSC-AD, CMP, CLP and GMP populations. b, Absolute numbers of CMP, CLP and GMP per mouse in Young (n=5), Aged-PBS (n=7) and Aged-yEOS (n=8) groups. c, Absolute numbers of CMP, CLP and GMP per mouse in Aged-PBS (n=8) and Aged-yEOSIL-4-/- (n=10) groups. One out of two independently performed experiments is shown. Statistical significance in (b) was calculated one-way ANOVA followed by two-tailed post-hoc Dunnett’s multiple comparison test against the aged-PBS treated group and (c) by two-tailed Student’s t-test. d, Gating strategy for the identification of germinal GCB. Data are shown as individual data points with mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001.

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