Extended Data Fig. 7: In vivo AMPKα1 conditional deletion in DRG neurons.

a, Representative images of AMPKα1 and GFP immunostaining in DRG sections 5 weeks following AAV-GFP or AAV-Cre-GFP sciatic nerve injection. Scale bar, 50 μm. b, Representative images of AMPKα2 and GFP immunostaining in DRG sections 5 weeks following AAV-GFP or AAV-Cre-GFP sciatic nerve injection. Arrowheads mark GFP positive neurons showing the presence or loss of AMPKα2 staining. Scale bar, 50 μm. c, Quantification of AMPKα1 level of (a). n = 3 mice. Values represent means ± SEM. Two-tailed unpaired Welch’s t-test. d, Quantification of AMPKα2 level of (b). n = 3 mice. Values represent means ± SEM. Two-tailed unpaired Welch’s t-test.