Extended Data Fig. 7: A decrease in eIF4E dose increases lipolysis and mitochondria numbers.
From: The major cap-binding protein eIF4E regulates lipid homeostasis and diet-induced obesity
a, Relative glycerol released from cells after 3 hr as an index of lipolysis levels in AML12 cells in basal condition or with 100 μM isoproterenol stimulation (n = 3, 3 independent replicates per group), mean ± SEM, ns = P > 0.05; *P = 0.016; by two-way ANOVA. Glycerol levels were normalized by cell number. b, Relative mitochondria abundance. (n = 3, 3 independent replicates per group), mean ± SEM, ns = P > 0.05; *P = 0.043; by two-way ANOVA.
