Extended Data Fig. 9: Single cell RNA-seq analysis of TPCs from 2 WT and 2 KO tumors.
From: A unique subset of glycolytic tumour-propagating cells drives squamous cell carcinoma
Extended Data Fig. 9 (related to Fig. 4). a, Dimensionality reduction analysis of prospectively isolated TPCs from 2 WT and 2 KO tumours using UMAP (resolution = 0.5), color-coded by clusters (top) or samples (bottom) b, Dimensionality reduction analysis of prospectively isolated TPCs from 2 WT and 2 KO tumours using tSNE, color-coded by clusters (top) or samples (bottom) c, Principal component analysis of prospectively isolated TPCs from 2 WT and 2 KO tumours, color-coded by samples d, Bar graph indicating cluster frequency by mouse samples. e,f, Dimensionality reduction analysis of prospectively isolated TPCs from 1 WT and 2 KO tumours using UMAP (resolution = 0.5, e) or tSNE (f), color-coded by samples g,h, Violin plots to show expression levels of Cd34 (g) or a6 integrin (h), shown by clusters (top) and samples (bottom) i,j, Trajectory analysis of TPCs, shown by clusters (i) or pseudotime (j).
