Extended Data Fig. 5: Additional positron emission tomography and secretin receptor gene expression results.

a, Brown adipose tissue (BAT) glucose uptake (GU) in cold and after secretin. There is no correlation between BAT GU in cold exposure and after secretin infusion. Data were analyzed by Spearman’s rank correlation in order to avoid assumptions around linearity of associations (n = 15). b, human secretin receptor (SCTR) expression on mRNA level, assessed by qPCR, in supraclavicular BAT is weakly associated with body-mass-index (BMI) in n = 14 fasted participants. Data were analyzed by Pearson’s correlation. c, SCTR expression analyzed by RNASeq does not correlate with BMI in n = 14 non-fasted participants. Data were analyzed by Pearson’s correlation.