Extended Data Fig. 9: Metabolic flux analysis of the cells with different mtDNA variants: HB(100%), HB(24%), BG(95%) and C57BL/6N. | Nature Metabolism

Extended Data Fig. 9: Metabolic flux analysis of the cells with different mtDNA variants: HB(100%), HB(24%), BG(95%) and C57BL/6N.

From: Cell competition acts as a purifying selection to eliminate cells with mitochondrial defects during early mouse development

Extended Data Fig. 9: Metabolic flux analysis of the cells with different mtDNA variants: HB(100%), HB(24%), BG(95%) and C57BL/6N.

a, OCR profile during mitochondria stress test performed in pluripotency maintenance conditions. b-i, Metabolic parameters assessed during the during the mitochondria stress test performed in pluripotency conditions. Data obtained from 3 independent experiments, with 5 replicates per cell type in each assay. Error bars represent SEM. See methods for details on statistical analysis.

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