Extended Data Fig. 2: Liver weight and histological assessment after 11 cycles of FMD.
From: Fasting-mimicking diet prevents high-fat diet effect on cardiometabolic risk and lifespan
Extended Data Fig. 2 related to Fig. 2. Liver weight and histological assessment after 11 cycles of FMD. a) Liver weight. One-way ANOVA, p = 0.0010***. Tukey’s multiple comparisons tests: Control vs. HFCD, p = 0.0399 *; Control vs. HFCD + FMD, p = 0.0007 ***; HFCD vs. HFCD + FMD, p = 0.2549 ns. Control (n = 6), HFCD (n = 4), HFCD + FMD (n = 6). Data are shown as the mean ± SEM. b) Liver weight to body weight ratio. One-way ANOVA, p = 0.0061. Tukey’s multiple comparisons tests: Control vs. HFCD, p = 0.0404 *; Control vs. HFCD + FMD, p = 0.4297 ns; HFCD vs. HFCD + FMD, p = 0.0048 **. Control (n = 6), HFCD (n = 4), HFCD + FMD (n = 6). Data are shown as the mean ± SEM. c) Liver histological score. One-way ANOVA, p = 0.2314 ns. Control (n = 12), HFCD (n = 11), HFCD + FMD (n = 8). Data are shown as the mean ± SEM. d) Steatosis score. One-way ANOVA, p = 0.4541 ns. Control (n = 12), HFCD (n = 11), HFCD + FMD (n = 8). Data are shown as the mean ± SEM.
