Table 3 Association of PDFF with PSD3 rs7003060 overall and within four BMI strata in white British participants from the UK Biobank

From: PSD3 downregulation confers protection against fatty liver disease

rs7003060

 

GG

GT

TT

   
 

N

Median (i.q.r.)

N

Median (i.q.r.)

N

Median (i.q.r.)

P value

Beta

CI

Overall

5,243

2.92 (2.78)

4,668

2.84 (2.71)

1,059

2.86 (2.67)

0.49

−0.00892

−0.034, 0.016

BMI < 25

2,137

2.18 (1.5)

1,907

2.19 (1.40)

442

2.22 (1.36)

0.77

−0.00636

−0.048, 0.035

25 ≤ BMI < 30

2,294

3.32 (2.94)

2,019

3.29 (3.10)

433

3.31 (2.85)

0.66

0.00975

−0.033, 0.052

30 ≤BMI < 35

651

4.86 (6.03)

568

4.25 (4.87)

143

4.72 (6.67)

0.18

−0.0534

−0.13, 0.025

BMI ≥ 35

156

6.37 (8.8)

165

5.14 (8.04)

39

5.60 (7.47)

0.02

−0.175

−0.33, −0.022

  1. Analysis was performed using a linear regression adjusted for age, sex, BMI, the first ten principal components of ancestry and array type.
Back to article page