Extended Data Fig. 6: Corroboration of HLA-DR+ Ductal cells. | Nature Metabolism

Extended Data Fig. 6: Corroboration of HLA-DR+ Ductal cells.

From: Single-cell multi-omics analysis of human pancreatic islets reveals novel cellular states in type 1 diabetes

Extended Data Fig. 6: Corroboration of HLA-DR+ Ductal cells.

(a-b) Dendrograms highlighting the expression of the MHC class II complex (a) or MHC class II activity (b) across the dendrogram of all cells in Fig. 1C. Scale bars represent normalized transcript numbers (mean across all MHC class II complex genes (a) or MHC class II activity genes (b)). (c-d) Dendrograms highlighting the expression of the MHC class II complex (c) or MHC class II activity (d) across the dendrogram of ductal and endocrine cells in Fig. 1D. Scale bars represent normalized transcript numbers (mean across all MHC class II complex genes (c) or MHC class II activity genes (d)). (e-f) Dendrograms highlighting the expression of the HLA-DPB1 (E) or KRT19 (f) across the dendrogram of ductal and endocrine cells in Fig. 1D. Scale bars represent normalized transcript numbers. (g) Dendrograms highlighting the expression of the immune-related genes across the dendrogram of ductal and endocrine cells in Fig. 1D. Scale bars represent normalized transcript numbers. (h) Dendrograms highlighting the expression of the BMPR1A across the dendrogram of ductal and endocrine cells in Fig. 1D. Scale bars represent normalized transcript numbers.

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