Extended Data Fig. 7: The effect of SZ0232 on db/db mice.
From: mPGES-2 blockade antagonizes β-cell senescence to ameliorate diabetes by acting on NR4A1
a-c, db/db mice were administered with saline or SZ0232 daily for 8 weeks and then sacrificed. a, Body weight (n = 5). b, Serum biochemistry parameters (n = 5). c, Representative pictures of H&E staining in different tissues (n = 4); scale bars = 20 μm. H&E staining was repeated more than twice, independently, and similar results were obtained. Data are expressed as mean ± SEM. Statistical significance was assessed using a two-tailed unpaired Student’s t-test.
