Extended Data Fig. 9: Loss of endothelial Pten results in increased label-free polyamine levels. | Nature Metabolism

Extended Data Fig. 9: Loss of endothelial Pten results in increased label-free polyamine levels.

From: Angiocrine polyamine production regulates adiposity

Extended Data Fig. 9: Loss of endothelial Pten results in increased label-free polyamine levels.

(a, b) Schematic representation of the polyamine metabolic pathway and expression of the indicated metabolites in (d) adipose endothelial cells (control n = 6, PteniΔEC n = 6) and (e) eWAT (control n = 8, PteniΔEC n = 7) measured by LCMS. Data represent mean ± SEM (error bars). Statistical analysis was performed by t-test (Extended Data Fig. 9a,b).

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