Extended Data Fig. 2: Labeling patterns of ribose-5-phosphate (a) and fructose-6-phosphate (b) from 1-13C-glucose (Related to Fig. 2). | Nature Metabolism

Extended Data Fig. 2: Labeling patterns of ribose-5-phosphate (a) and fructose-6-phosphate (b) from 1-13C-glucose (Related to Fig. 2).

From: Switching to the cyclic pentose phosphate pathway powers the oxidative burst in activated neutrophils

Extended Data Fig. 2

Labeling patterns were measured in neutrophils stimulated with PMA (100 nM) for 30 min, with or without the treatment of NOX inhibitor DPI (10 µM). Bar graphs show the mean value from two technical replicates (indicated by dots). Results have been confirmed in three independent experiments. Labeling patterns of selected other metabolites are shown in Fig. 2. *F6P peak may contain some glucose-1-phosphate, as these two compounds are not fully resolved on LCMS.

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