Extended Data Fig. 1: α-adrenergic receptor expression in murine and human adipose tissues.
From: ADRA1A–Gαq signalling potentiates adipocyte thermogenesis through CKB and TNAP
a, Ribosomal profiling of candidate GPCRs from SAT and BAT of 30 °C-acclimated mice14 (n = 5 per tissue). b, Ribosomal profiling from TRAP13 of α1AR and α2AR subtypes from different tissues in mice (BAT: n = 3, PgAT: n = 3, SAT: n = 3, QUAD muscle: n = 4). c-e, Relative mRNA expression of (c) ADRB1, (d) PTGER1 and (e) CXCR7 from human BAT (adipose tissue proximal to carotid sheath) (n = 10) and paired SAT (n = 10), first cohort. Data are presented as mean ± s.e.m. and n numbers are of biologically independent experiments. a, c-e, two-tailed student’s t-tests; b, one-way ANOVA (Fisher’s LSD).
