Extended Data Fig. 2: LDHA displayed a much weaker interaction with Rac1-T35S mutant compared with WT Rac1 in cells.
From: Metabolic enzyme LDHA activates Rac1 GTPase as a noncanonical mechanism to promote cancer
Hs578T cells with ectopic expression of LDHA-Flag and WT Myc-Rac1, Myc-Rac1-T17N, or Myc-Rac1-T35S were employed for co-IP assays followed by western-blot assays. Data represent three repeats with similar results.
