Extended Data Fig. 2: LDHA displayed a much weaker interaction with Rac1-T35S mutant compared with WT Rac1 in cells. | Nature Metabolism

Extended Data Fig. 2: LDHA displayed a much weaker interaction with Rac1-T35S mutant compared with WT Rac1 in cells.

From: Metabolic enzyme LDHA activates Rac1 GTPase as a noncanonical mechanism to promote cancer

Extended Data Fig. 2: LDHA displayed a much weaker interaction with Rac1-T35S mutant compared with WT Rac1 in cells.The alternative text for this image may have been generated using AI.

Hs578T cells with ectopic expression of LDHA-Flag and WT Myc-Rac1, Myc-Rac1-T17N, or Myc-Rac1-T35S were employed for co-IP assays followed by western-blot assays. Data represent three repeats with similar results.

Source data

Back to article page