Extended Data Fig. 3: Change of the core body temperature and metabolic rate in the off-target groups.
From: Induction of a torpor-like hypothermic and hypometabolic state in rodents by ultrasound
Change of the core body temperature relative to the baseline (ΔTcore) and the calculated max ΔTcore for the four groups, including the group without ultrasound stimulation (US−), the group receiving ultrasound stimulation at the POA (POA), the off-target control group receiving ultrasound at the cortex (Cortex), and the off-target control group receiving ultrasound at the ventral hippocampus (Hippocampus). In the right figure, max ΔTcore was calculated as lowest Tcore – mean Tcore before US. US sonication is indicated by the pink bar. Solid lines and shadows denote the mean ± s.e.m. Error bars denote s.e.m. Each dot represents one mouse. N = 8 mice in the US−group, 7 mice in the POA group, 4 mice in the Cortex group and 6 mice in the Hippocampus group. P values were calculated using a one-way ANOVA followed by Dunnett’s post-hoc test comparing each group to US−.
