Extended Data Fig. 3: General features and circadian clock oscillation of the multi-omics dataset.
From: Daytime-restricted feeding enhances running endurance without prior exercise in mice
a, Exercise performance in 1-week TRF mice as measured by time to exhaustion (n = 16 mice). b, Workflow of the multi-omics study. c-d, Diurnal expression of the muscle clock genes in TRF mice (c, female: n = 4 mice; d, male: n = 4 mice). e, Phase distribution of oscillating muscle genes and phase-shift between dual-oscillating genes in TRF mice. f-h, Diurnal expression of dual-oscillating (f), DRF-only (g), NRF-only (g), and mitochondrial (h) rhythmic genes in skeletal muscle (n = 4 mice per time-point). Data were represented as the mean ± s.e.m. or minima, maxima, median, 25th and 75th percentiles. Statistical test: ANOVA, two-sided unpaired Student’s t-test with Bonferroni correction, MetaCycle: P-values from JTK and LS methods were adjusted by Fisher’s method.
