Table 2 Participant data from study in normal weight and obese healthy volunteers
From: The serotonin transporter sustains human brown adipose tissue thermogenesis
Normal weight (n = 10) | Obese (n = 10) | P value | |
|---|---|---|---|
Age (years) | 28.3 ± 2.1 | 28.2 ± 2.1 | 0.982 |
Sex | 5 males, 5 females | 4 males, 6 females | |
BMI (kg m−2) | 21.5 ± 0.4 | 36.2 ± 1.3 | 4.20 × 10−9 |
Fat mass (kg) | 10.9 ± 1.1 | 38.1 ± 2.3 | 2.45 × 10−9 |
Fat percentage (%) | 17.3 ± 2.0 | 35.8 ± 2.0 | 3.99 × 10−6 |
Systolic blood pressure (mmHg) | 121 ± 3 | 129 ± 4 | 0.143 |
Diastolic blood pressure (mmHg) | 72 ± 3 | 80 ± 3 | 0.069 |
Outdoor temperature (°C) | 8.4 ± 1.4 | 7.3 ± 1.5 | 0.591 |
Warm room temperature (°C) | 23.7 ± 0.3 | 23.5 ± 0.1 | 0.496 |
Cold room temperature (°C) | 16.0 ± 0.2 | 16.1 ± 0.1 | 0.690 |
Indirect calorimetry data | |||
EE in warm (kcal d−1) | 1,477 ± 81 | 1,897 ± 101 | 0.004 |
EE in cold (kcal d−1) | 1,635 ± 85* | 1,984 ± 84 | 0.009 *0.008 |
CIT (kcal d−1) | 158 ± 47 | 86 ± 52 | 0.322 |
Thermal imaging data | |||
Supraclavicular skin temperature in warm (°C) | 35.4 ± 0.1 | 34.7 ± 0.1 | 6.18 × 10−4 |
Supraclavicular skin temperature in cold (°C) | 34.4 ± 0.2 | 33.4 ± 0.2 | 8.40 × 10−4 |
Sternal temperature in warm (°C) | 34.3 ± 0.2 | 33.6 ± 0.2 | 0.028 |
Sternal temperature in cold (°C) | 32.7 ± 0.3 | 31.0 ± 0.3 | 0.002 |
Cold-induced change in supraclavicular temperature (°C) | -1.0 ± 0.1 | -1.4 ± 0.2 | 0.061 |
Cold-induced change in sternal temperature (°C) | -1.7 ± 0.2 | -2.6 ± 0.2 | 0.002 |
Temperature differential between supraclavicular and sternum in warm (°C) | 1.1 ± 0.2 | 1.1 ± 0.2 | 0.788 |
Temperature differential between supraclavicular and sternum in cold (°C) | 1.7 ± 0.3 | 2.4 ± 0.3 | 0.157 |
Cold-induced change in temperature differential (°C) | 0.7 ± 0.1 | 1.2 ± 0.2 | 0.018 |
