Extended Data Fig. 8: Transcriptome analysis of primary hepatocytes from WT and WDR6-WKO mice, related to Fig. 3. | Nature Metabolism

Extended Data Fig. 8: Transcriptome analysis of primary hepatocytes from WT and WDR6-WKO mice, related to Fig. 3.

From: Upregulation of WDR6 drives hepatic de novo lipogenesis in insulin resistance in mice

Extended Data Fig. 8: Transcriptome analysis of primary hepatocytes from WT and WDR6-WKO mice, related to Fig. 3.The alternative text for this image may have been generated using AI.

a, A volcano plot showing differentially expressed genes in WDR6-WKO vs. WT groups. Red, upregulated genes; blue, downregulated genes, gray, no significant change. b, Heat map of differentially expressed genes in WDR6-WKO vs. WT groups. n = 3 biologically independent mice per group. c, Reactome enrichment analysis of differentially expressed genes in WDR6-WKO vs. WT groups. d, GO enrichment analysis of up-regulated genes in WDR6-WKO vs. WT groups. e, GO enrichment analysis of down-regulated genes in WDR6-WKO vs. WT groups.

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