Extended Data Fig. 7: Physiology phenotypes of 4-week and 8-week ob/ob mice. | Nature Metabolism

Extended Data Fig. 7: Physiology phenotypes of 4-week and 8-week ob/ob mice.

From: Readily releasable β cells with tight Ca2+–exocytosis coupling dictate biphasic glucose-stimulated insulin secretion

Extended Data Fig. 7: Physiology phenotypes of 4-week and 8-week ob/ob mice.

a, b, The glucose tolerance test (a) and body weight (b) of 4w and 8w ob/ob mice and their littermates. n = 12 mice (6 male and 6 female) from 4w Ins-GCaMP ob/wt mice, 10 mice (5 male and 5 female) from 4w Ins-GCaMP ob/ob mice, 5 male mice from 8w wt/wt and 5 male mice from 8w ob/ob mice. Data was expressed as mean ± s.e.m., p values were analyzed by two-sided unpaired Student’s t-tests, *p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.

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