Extended Data Table 5 Association of serum trigonelline levels with muscle mRNA expression of demethylase and methyltransferase genes in the Singapore Sarcopenia Study

From: Trigonelline is an NAD+ precursor that improves muscle function during ageing and is reduced in human sarcopenia

  1. Serum trigonelline levels measured with LC–MS/MS in the Singapore Sarcopenia study of MEMOSA was associated with gene expression measured using RNA sequencing in muscle biopsies, analysed with a Spearman rank correlation, filtered for genes expressed in skeletal muscle and annotated with methyltransferase or demethylase activity.
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