Fig. 1: Z-spectral fitting of adipose tissues producing multi-parametric contrasts including Cr-CEST.
From: Non-invasive mapping of brown adipose tissue activity with magnetic resonance imaging
a–c, Fitting of the Z-spectra of BAT under different pre-saturation durations: 1.0 μT for 1.0 s (a), 2.0 s (b) and 3.0 s (c). The Cr-CEST peaks (red arrows) could be observed visually. d,e, Z-spectra of WAT (d) and muscle (e) under a 1.0 μT saturation for 3.0 s. f,g, Demonstration of the selection of image slices from the axial (f) and sagittal (g) views of rats’ interscapular fat depots, representative structural T2-weighted images and the corresponding FWF, Cr-CEST and APT maps obtained from the Z-spectral fitting. Representative image from n = 6. In the T2-weighted images, the arrowheads point to the BAT, WAT and muscle regions, respectively.
