In this issue of Nature Metabolism, Carrasco-Zanini et al. describe sets of modifiable and non-modifiable drivers of human plasma proteins. These findings may inform the design of precision prevention programs and highlight novel therapeutic targets.
This is a preview of subscription content, access via your institution
Access options
Access Nature and 54 other Nature Portfolio journals
Get Nature+, our best-value online-access subscription
$32.99 / 30 days
cancel any time
Subscribe to this journal
Receive 12 digital issues and online access to articles
$119.00 per year
only $9.92 per issue
Rent or buy this article
Prices vary by article type
from$1.95
to$39.95
Prices may be subject to local taxes which are calculated during checkout

References
Snow, J. J. Public Health Sanit. Rev. 2, 239–257 (1856).
Franks, P. W. & Pomares-Millan, H. Diabetologia 63, 2521–2532 (2020).
Carrasco-Zanini, J. et al. Nat. Metab. https://doi.org/10.1038/s42255-024-01133-5 (2024).
Kurgan, N., Kjærgaard Larsen, J. & Deshmukh, A. S. Diabetologia 67, 783–797 (2024).
Bailey, R. L. Curr. Opin. Biotechnol. 70, 91–96 (2021).
Bar, N. et al. Nature 588, 135–140 (2020).
Asnicar, F. et al. Nat. Med. 27, 321–332 (2021).
Oh, H. S. et al. Nature 624, 164–172 (2023).
Argentieri, M. A. et al. Nat. Med. (2024).
Acknowledgements
P.W.F. and D.E.C. were supported by grants from the Swedish Research Council (2019-01348), the Swedish Foundation for Strategic Research (LUDC-IRC, 15-0067) and the European Commission (ERC-CoG_NASCENT - 681742).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing interests.
Rights and permissions
About this article
Cite this article
Franks, P.W., Coral, D.E. Causal drivers of human proteome variation in health and disease. Nat Metab 6, 1854–1855 (2024). https://doi.org/10.1038/s42255-024-01138-0
Published:
Version of record:
Issue date:
DOI: https://doi.org/10.1038/s42255-024-01138-0