The gut–liver axis is of crucial importance in health and disease. TM6SF2 is a genetic risk factor for metabolic dysfunction-associated steatotic liver disease. Zhang, Yu et al. reveal that intestinal TM6SF2 critically affects the gut–liver axis.
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Tilg, H., Grander, C. TM6SF2 as new intestinal lipid player. Nat Metab 7, 4–5 (2025). https://doi.org/10.1038/s42255-024-01156-y
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DOI: https://doi.org/10.1038/s42255-024-01156-y
