Extended Data Fig. 3: Gut microbiome and YFAS components. | Nature Metabolism

Extended Data Fig. 3: Gut microbiome and YFAS components.

From: Microviridae bacteriophages influence behavioural hallmarks of food addiction via tryptophan and tyrosine signalling pathways

Extended Data Fig. 3

ANCOM-BC microbiome differential abundance (two-sided Z-test using the statistic W = log2Fold Change/standard error) volcano plot at the family level for a) YFAS in the discovery cohort (IRONMET-CGM) and b) for YFAS in the validation cohort 1 (IRONMET); c) YFAS motivation, d) YFAS persistence, e) YFAS compulsivity for the discovery cohort IRONMET-CGM; f) YFAS motivation, g) YFAS persistence, h) YFAS compulsivity for the validation cohort IRONMET. Fold change associated with a unit change in the YFAS score and log10 p values adjusted for multiple testing are plotted for each family. All analyses were performed controlling for age, waist circumference, sex (only when individuals of both sexes were included in the analysis), and education years as covariates.

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