Extended Data Fig. 10: Deletion of dHPCFat neurons decreases meal size in the dark phase. | Nature Metabolism

Extended Data Fig. 10: Deletion of dHPCFat neurons decreases meal size in the dark phase.

From: Separate orexigenic hippocampal ensembles shape dietary choice by enhancing contextual memory and motivation

Extended Data Fig. 10: Deletion of dHPCFat neurons decreases meal size in the dark phase.

A Dark phase meal pattern analysis of 45% HFHS diet in dHPCSugar mice with viral-mediated ablation (N = 11-12/group, Unpaired Student’s t test). B Light phase meal pattern analysis of 45% HFHS diet in dHPCSugar mice with viral-mediated ablation (N = 11-12/group, Unpaired Student’s t test). C Comparing percent weight gain at 2 and 4 weeks between dHPCSugar mice with viral-mediated ablation (N = 9/group, Two-way ANOVA with Holm-Sidak post hoc analysis). D Comparing percent fat mass accumulation at 2 and 4 weeks between dHPCSugar mice with viral-mediated ablation (N = 9/group, Two-way ANOVA with Holm-Sidak post hoc analysis). E Cumulative hourly food intake in control mice in response to saline and CNO (N = 5, Two-way RM ANOVA with Holm-Sidak post-hoc analysis).

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