Extended Data Fig. 2: In the absence of choice, fat responsive dHPC neurons increase fat intake independently of taste. | Nature Metabolism

Extended Data Fig. 2: In the absence of choice, fat responsive dHPC neurons increase fat intake independently of taste.

From: Separate orexigenic hippocampal ensembles shape dietary choice by enhancing contextual memory and motivation

Extended Data Fig. 2: In the absence of choice, fat responsive dHPC neurons increase fat intake independently of taste.

A Number of sucrose responsive neurons in the dHPC using FosTRAP and Fos immunohistochemistry (N = 6, Paired Student’s t test) B Number of fat responsive neurons in the dHPC using FosTRAP and Fos immunohistochemistry (N = 6, Paired Student’s t test). C Percent overlap between neurons responding to repeated IG fat infusions compared to separate macronutrients in the dDG. (N = 5/group, unpaired t test). D Proportion of GABA-expressing neurons colocalized with tdTomato positive neurons trapped with IG infusion of sucrose (left) or fat (right). E Proportion of vGLUT1-expressing neurons colocalized with tdTomato positive neurons trapped with IG infusion of sucrose (left) or fat (right). Data are presented as mean ± s.e.m. **** P < 0.0001, ns, not significant.

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