Fig. 1: Dietary fat source influences growth of B16 melanoma tumours in obesity.
From: The source of dietary fat influences anti-tumour immunity in obese mice
a, Schematic of experimental design. b–g, Body weight (left) and tumour volumes (right) of subcutaneous B16-F10 melanoma tumours in mice fed a SFD (13% fat) or HFD (45% fat) from various plant and animal fat sources for 12 weeks. HFDs were derived mostly from lard (b), beef tallow (c), butter (d), coconut oil (e), olive oil (f) or palm oil (g); n = 5, representative of three (b), two (c), four (d), three (e), two (f) and four (g) independent experiments. SFD control groups are the same in (b, d, e, g) and (c, f). In bar graphs, bar height represents the mean; error bars, s.e.m. In line graphs, each data point represents the mean; error bars, s.e.m. Comparisons were made using the two-tailed Mann–Whitney test (b–g, left) or two-way repeated-measures ANOVA followed by Bonferroni’s multiple comparisons test (b–g, right). Created in BioRender.com.
