Fig. 7: The Neurolipid Atlas.

Overview of the Neurolipid Atlas data commons (https://neurolipidatlas.com) to explore all lipidomics datasets from this study. A representative image of the homepage is shown, where one can proceed to a list of experiments by selecting one of the cell type, human or mouse icons or enter a search term as indicated in the top panel. Alternatively, a list of all datasets can be found by selecting; ‘go to all datasets. A link to the quick start guide can be found at the bottom of the homepage or behind the menu (≡) icon in the top right corner. To explore data, experiments can be selected in the dataset browser window as indicated. Independent replicates of the experiment can be selected in the left column under ‘data’. Visualization options can be (de)selected in the top horizontal bar. Examples of bar graphs, volcano plots and heat maps for visualization of changes in lipid class (bar graphs) or lipid species (volcano plots and heat maps) levels between selected conditions are shown. The ‘QC’ and ‘help’ modules present in the left column offer extensive background information on the QC, data-processing steps, lipid class measurements and visualization options. Lastly, a summary list of currently available datasets is shown.