Extended Data Fig. 1: Polygenic Score difference from controls restricted to probands only. | Nature Metabolism

Extended Data Fig. 1: Polygenic Score difference from controls restricted to probands only.

From: Common genetic variants modify disease risk and clinical presentation in monogenic diabetes

Extended Data Fig. 1

Mean polygenic score difference for MODY probands (orange, N = 924) compared to controls (dashed black line, N = 7645). Scores are standardized, with controls set to a mean of 0 and a standard deviation of 1. Error bars indicate 95% confidence intervals, and dots represent the mean estimates, determined by linear regression models adjusted for the first ten within-cohort principal components.

Source data

Back to article page