Extended Data Fig. 2: Polygenic Score difference from controls by HNF MODY subtype.
From: Common genetic variants modify disease risk and clinical presentation in monogenic diabetes
Mean polygenic score differences for HNF1A (pink, N = 997), HNF1B (blue, N = 145), and HNF4A (green, N = 320) carriers compared to controls (dashed black line, N = 7645), as determined by linear regression models adjusted for the first ten within-cohort principal components. Scores are standardized, with controls set to a mean of 0 and a standard deviation of 1. Error bars represent 95% confidence intervals, and dots denote the mean estimates.
