Extended Data Fig. 9: SLC25A51 overexpression is associated with changes in amino acid metabolism and pantothenate and CoA biosynthesis in mitochondria from regenerating livers. | Nature Metabolism

Extended Data Fig. 9: SLC25A51 overexpression is associated with changes in amino acid metabolism and pantothenate and CoA biosynthesis in mitochondria from regenerating livers.

From: Hepatocyte mitochondrial NAD+ content is limiting for liver regeneration

Extended Data Fig. 9

a, Altered metabolites in isolated mitochondria from SLC25A51 overexpressing vs. control livers during regeneration. Significant metabolites were determined by p < 0.05 from an unpaired two-tailed Student’s t-test. Metabolites with a P value less than 0.05 are colored in red (upregulated) or in green (downregulated). b, Pathway enrichment based on significantly altered metabolites (P  < 0.05 from Student’s t-test) in isolated mitochondria from regenerating SLC25A51 overexpressing livers vs. eGFP controls.

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