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Skeletal muscle

A dedicated recycling bin keeps muscle healthy

Nature Metabolism volume 7, pages 2390–2392 (2025)Cite this article

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Two studies in Nature Metabolism reveal a critical role of chaperone-mediated autophagy in maintaining homeostasis and promoting regeneration of skeletal muscle.

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Fig. 1: Schematic representation of CMA.

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Acknowledgements

Work in the Sartorelli lab is supported by National Institutes of Health grants AR041164-18 and AR041126-26.

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Authors and Affiliations

  1. Laboratory of Muscle Stem Cells & Gene Regulation, Bethesda, MD, USA

    Vittorio Sartorelli

  2. National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD, USA

    Vittorio Sartorelli

  3. National Institutes of Health, Bethesda, MD, USA

    Vittorio Sartorelli

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  1. Vittorio Sartorelli
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Correspondence to Vittorio Sartorelli.

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Sartorelli, V. A dedicated recycling bin keeps muscle healthy. Nat Metab 7, 2390–2392 (2025). https://doi.org/10.1038/s42255-025-01418-3

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