Extended Data Fig. 3: Hierarchical clustering. | Nature Metabolism

Extended Data Fig. 3: Hierarchical clustering.

From: Multi-omics profiling of cachexia-targeted tissues reveals a spatio-temporally coordinated response to cancer

Extended Data Fig. 3

See also Fig. 1a for experimental setup. Ctrl: healthy controls, no tumour; Non-cax: non-cachectic tumour mice; Pre-cax: pre-cachectic tumour mice; Cax: cachectic tumour mice. n = 4 animals per group. Hierarchical clustering across all tissues and detected metabolites based on the log2 fold changes for each tissue sample of tumour mice compared to Ctrl. Key metabolites driving the clustering, and altered in cachexia-target tissues, are highlighted.

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