Extended Data Fig. 9: Deletion of Bmal1 leads to impaired glucose tolerance on a chow diet, which is prevented by NDI1, related to Fig. 4.
From: Adipocyte NADH dehydrogenase reverses circadian and diet-induced metabolic syndrome
a, Body weight of Control, Bmal1-KO, and Bmal1-KO + NDI1 mice at 4 months of age on a chow diet (n = 7 Control, n = 6 Bmal1-KO, and n = 5 Bmal1-KO + NDI1). b, Glucose tolerance test (GTT) and insulin during the GTT of the mice in A at 4 months of age (n = 7 Control, n = 6 Bmal1-KO, and n = 5 Bmal1-KO + NDI1). Data are represented as mean ± SEM. Statistical significance was calculated by one-way ANOVA in a and two-way ANOVA followed by Dunnett’s multiple comparisons test with Bmal1-KO mice set as the reference group in b. # denotes statistical significance between Bmal1-KO vs other groups (p < 0.05).
